ACTN3 R577X polymorphism in top-level Polish rowers
نویسندگان
چکیده
منابع مشابه
Association of the ACTN3 R577X Polymorphism in Polish Power-Orientated Athletes
Alpha-actinins are an ancient family of actin-binding proteins that play structural and regulatory roles in cytoskeletal organization. In skeletal muscle, α-actinin-3 protein is an important structural component of the Z disc, where it anchors actin thin filaments, helping to maintain the myofibrillar array. A common nonsense polymorphism in codon 577 of the ACTN3 gene (R577X) results in α-acti...
متن کاملThe ACTN3 R577X polymorphism in East and West African athletes.
PURPOSE To determine the frequency of the ACTN3 R577X polymorphism (functional R allele and nonfunctional X allele) in a variety of African populations and to examine its influence on the success of elite East African endurance runners and West African sprinters. METHODS The R577X polymorphism was genotyped in 198 Ethiopian controls and 76 elite Ethiopian endurance athletes, 158 Kenyan contro...
متن کاملACTN3 R577X Polymorphism and Neuromuscular Response to Resistance Training.
The R577X polymorphism at the ACTN3 gene has been associated with muscle strength, hypertrophy and athletic status. The X allele, which is associated with the absence of ACTN3 protein is supposed to impair performance of high force/velocity muscle contractions. The purpose of the present study was to investigate the association of the R577X polymorphism with the muscle response to resistance tr...
متن کاملThe GABPB1 gene A/G polymorphism in Polish rowers
Nuclear respiratory factor 2 (NRF2), also referred to as the GA-binding protein (GABP) transcription factor, is a key transcriptional activator of many nuclear genes which encode a wide range of mitochondrial enzymes. The variants of the GABPB1 gene encoding the beta1 subunit of NRF2 protein have been associated with physical performance, particularly endurance. The aim of this study was to con...
متن کاملPrevalence of ACTN3 (the athlete gene) R577X polymorphism in Iranian population
BACKGROUND Ability of athletes in speed or endurance contests somehow is determined by inherited muscle fiber types. One of the important genes involved in sport genetics is ACTN3 that is located on chromosome 11q13-q14 and encodes α-actinin-3, which belongs to highly conserved family of α-actinin proteins. Genetic analysis of α-actinin-3 gene has showed a polymorphism R577X (rs1815739), which ...
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ژورنال
عنوان ژورنال: Journal of Exercise Science & Fitness
سال: 2012
ISSN: 1728-869X
DOI: 10.1016/j.jesf.2012.04.003